How to Spend a Perfect Weekend in Santa Fe, New Mexico: The Ultimate 2-Day Itinerary
Rich with culture, creativity, and Southwest flavor, Santa Fe is one of the most charming cities in the U.S. Known for its adobe architecture, vibrant art galleries, and standout food scene, it's the kind of destination where two days can feel both relaxing and inspiring. Whether you're planning a weekend in Santa Fe as a romantic getaway, road trip from Albuquerque, or part of a New Mexico itinerary, this guide has you covered.
Weekend In Santa Fe, New Mexico
Stay
Rosewood Inn of the Anasazi
For a centrally located and luxurious stay, check into Rosewood Inn of the Anasazi. Just steps from the Santa Fe Plaza, this upscale boutique hotel blends Southwestern design with top-tier service. Expect cozy fireplaces, handcrafted furnishings, and easy access to all the city’s top spots. It’s one of the best hotels in downtown Santa Fe for a luxury weekend.
Allure Travel Co. Tip: At Allure Travel Co., we have partnerships with thousands of hotels around the world. Booking a stay through us is a complimentary service-meaning no extra cost to you! Not only will you save valuable time, but you’ll also unlock exclusive perks (like hotel credits and complimentary room upgrades, if available) and experience VIP treatment throughout your stay.
Santa Fe Itinerary: Day 1
Breakfast at Plaza Café
Start your weekend off with a local staple: Plaza Café in downtown Santa Fe. Don’t miss the Blue Corn Piñon Pancakes or the classic Huevos Rancheros, both crowd favorites with a local twist.
Walk Around the Santa Fe Plaza
This historic plaza has been the heartbeat of the city for over 400 years. Take a relaxed stroll, browse artisan stalls, and soak up the atmosphere. It’s one of the top things to do in Santa Fe for first-time visitors.
Cathedral Basilica of St. Francis of Assisi
Just steps from the plaza, this stunning cathedral blends Romanesque architecture with deep-rooted history. Free to enter and peaceful to wander, it’s a must-visit for architecture lovers.
Cross of the Martyrs
For beautiful city views, head to the Cross of the Martyrs. It’s a quick 10-minute walk uphill and a perfect photo spot, especially in the early morning or golden hour.
Lunch at The Shed
A Santa Fe icon since 1953, The Shed serves up award-winning New Mexican cuisine. Go for the red or green chile enchiladas (or “Christmas-style” if you want both), or the flavorful Carne Adovada. This spot doesn’t take reservations, so arriving before or after peak hours is your best bet.
Visit the Georgia O’Keeffe Museum
Celebrate one of America’s most iconic artists at the Georgia O’Keeffe Museum, home to more than 3,000 works. Even for non-museum people, the curation and storytelling here are unforgettable.
Explore Canyon Road
Calling all art lovers… Canyon Road features more than 100 art galleries showcasing everything from contemporary to traditional works. The street itself feels like an open-air museum, with charming adobe studios and sculpture gardens tucked around every corner.
Dinner at Geronimo
Wrap up your first day at Geronimo, a high-end spot housed in a 1756 adobe building on Canyon Road. Try the elk tenderloin or seared scallops, and don’t skip the curated wine list. It’s one of the best restaurants in Santa Fe for a date night or celebratory dinner.
Santa Fe Itinerary: Day 2
Breakfast at Café Pasqual’s
This cozy, colorful café is a Santa Fe legend. Everything is organic and locally sourced, and the chilaquiles are delicious. Expect a bit of a wait, but it’s always worth it.
Visit Meow Wolf Santa Fe
Meow Wolf is part immersive exhibit, part interactive story. It’s one of the most popular things to do in Santa Fe, and ideal for all ages. Book tickets online in advance.
Lunch at The Pantry
For hearty comfort food with a nostalgic diner vibe, head to The Pantry, a local favorite since 1948. The green chile cheeseburger and enchiladas are can’t-miss, and the prices are super reasonable.
Margarita Trail
Yes, it’s a real thing. The Santa Fe Margarita Trail features over 40 restaurants and bars, each offering a signature take on the iconic margarita. Grab a Margarita Passport, collect stamps as you sip your way through town, and score a fun souvenir if you hit enough stops. Local favorites include versions with prickly pear, smoked salt, and even green chile.
Sunset Drinks at The Bell Tower Bar
End the day with a cocktail and a sunset view at the Bell Tower Bar, perched atop La Fonda on the Plaza. The rooftop views stretch over the mountains, and the vibe is casual yet upscale, ideal for golden hour.
Dinner at Sazón
For an unforgettable dinner in downtown Santa Fe, head to Sazón, one of the city’s best fine dining restaurants. Highlights include the Sopa de Amor, a rich lobster bisque, and an array of house-made moles. Located just a few blocks from the Plaza, it’s the perfect spot for a romantic or celebratory evening. Reservations are highly recommended.
Bonus Experiences (If You Have More Time)
If your Santa Fe weekend getaway turns into a long weekend, here are a few worthy add-ons:
-Hike at Bandelier National Monument for ancient cliff dwellings and scenic trails
-Day trip to Taos, an artsy mountain town with a bohemian vibe
-Ojo Caliente Mineral Springs, a dreamy spa retreat just under an hour away
Interested in booking a trip to Santa Fe?
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